Contents:
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Major global public health challenges include neurological and mental health disorders, which weaken the brain, change a person’s behaviour and impair its ability to accomplish everyday tasks. Modern medications provide costly symptomatic treatment for neurological illnesses but have negative effects. So, people are turning to herbal remedies in search of superior treatments that are less expensive and have fewer negative effects. Mental health has been a very important topic in past in Unani System of Medicine and also its importance may not be refused today. Majority of toxins and disease-causing biological agents harm our essential organs; impair immune systems, results in complications and death. There is a need for medications that protect internal organs, preserve physiological functions and provide time and energy to recover from negative consequences. One distinctive aspect of the Unani medical approach is the use of tonics. Numerous herbal medications have been recommended by Unani physicians as Muqawiyat (tonics) to sculpt the body’s essential organs shielding them from toxins/illnesses and enhance bodily processes. Muqawiyat are non-toxic drugs having the power to sustain and improve human health when used consistently over an extended period of time. In the current review some single herbal drugs mentioned as Brain Tonics (Muqawwi-e-Dimag) in Unani literature have been discussed and their pharmacological properties like antioxidant, neuroprotective, anti-inflammatory, immunomodulatory, memory enhancing have been screened out which can provide a scientific reason and possible mechanism by which action of these Unani drugs as brain tonics can be interpreted with modern aspects.
Reproductive diseases are the leading cause of death among the female population and the medication provided or the therapeutics used conventionally for the treatment of those conditions leads to various side effects which downplays the efficacy of the drugs and here, the use of medical plants plays a pivotal role. Medical plants consist of various phytochemicals which have therapeutic properties that are found to be useful in the treatment of various disorders related to the female reproductive system, without causing any severe side effects. It has been found that the use of various phytochemicals, medical plants, or herbal formulas along with Western medicine results in increased treatment efficiency, which further proves the importance of using herbs and medical plants as therapeutics. This paper discusses the importance of these herbal medicines and formulas in treating female reproductive disorders evidenced by the discussion of various medical systems such as “Ayurveda” and “Traditional Chinese Medicine (TCM)” that rely on herbs for the treatment of such disorders and conditions. A table discussing various therapeutic herbs related to various disorders in relevance to the targeted organ of the female reproductive system is also discussed in this paper.
Background
Herbal medicines hold significant importance in traditional healthcare practices. As per the World Health Organization (WHO), approximately 70-80% of the world's population relies on traditional remedies to meet their healthcare requirements. Herbs are commonly used for both treatment and prevention of various diseases. However, growing interest in herbal products has raised concerns about their safety. While often perceived as harmless due to their natural origin, instances of toxicity and adverse effects have been reported. As per WHO guidelines, it is essential to conduct safety assessments of herbal medicines and food products to identify potential risks arising from environmental or soil contaminants.
Materials and Methods
Plants are prone to contamination by harmful substances. This study involved evaluating the safety profile of Centaurea behen Linn from the Asteraceae family by analyzing microbial load, heavy metal content through Atomic Mass Spectroscopy (AMS), aflatoxins via Liquid Chromatography-Tandem Mass Spectrometry, and pesticide residues using Gas Chromatography-Tandem Mass Spectrometry.
Results
Findings revealed that heavy metals such as lead, cadmium, mercury, and arsenic were within acceptable limits as outlined by WHO standards. Furthermore, no Aflatoxins, pesticide residues, or microbial contamination were detected in the crude drug sample.
Conclusion
The safety evaluation indicates that Centaurea behen Linn. is safe for use, with no evidence of toxicity risks.
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